Neuroleptic drug effect on plasma dopamine-beta-hydroxylase in schizophrenia.

Abstract

Plasma dopamine-beta-hydroxylase (DBH) activity was determined in 8 chronic schizophrenic patients following neuroleptic treatment for 2 months. Enzyme activity was decreased by 13.7 +/- 3.4% (mean +/- SD). The difference from pre-drug levels was not statistically significant. The reduction in DBH activity stabilized after the 1st month of treatment and was unrelated to neuroleptic drug load.

Cite this paper

@article{Baron1982NeurolepticDE, title={Neuroleptic drug effect on plasma dopamine-beta-hydroxylase in schizophrenia.}, author={Miron Baron and R S Gruen and Morton Levitt and John M Kane}, journal={Neuropsychobiology}, year={1982}, volume={8 6}, pages={312-4} }