Neuroleptic Malignant Syndrome and Atypical Antipsychotic Drugs

  title={Neuroleptic Malignant Syndrome and Atypical Antipsychotic Drugs},
  author={Jambur Ananth and Sharat G. Parameswaran and Sarath Gunatilake and Karl S Burgoyne and Taghrid Sidhom},
  journal={The Journal of clinical psychiatry},
  volume={65 4},
OBJECTIVE The incidence of neuroleptic malignant syndrome (NMS) is not known, but the frequency of its occurrence with conventional antipsychotic agents has been reported to vary from 0.02% to 2.44%. DATA SOURCES MEDLINE search conducted in January 2003 and review of references within the retrieved articles. DATA SYNTHESIS Our MEDLINE research yielded 68 cases (21 females and 47 males) of NMS associated with atypical antipsychotic drugs (clozapine, N = 21; risperidone, N = 23; olanzapine, N… CONTINUE READING


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