Neurokinin B and its receptor in hypogonadotropic hypogonadism.

@article{Semple2010NeurokininBA,
  title={Neurokinin B and its receptor in hypogonadotropic hypogonadism.},
  author={Robert K Semple and Ali kemal Topaloglu},
  journal={Frontiers of hormone research},
  year={2010},
  volume={39},
  pages={
          133-41
        }
}
The hypothalamus integrates multiple environmental and developmental cues relevant to reproductive function, serving to transduce these into a pulsatile output of gonadotropin-releasing hormone (GnRH). Although neuroanatomical and physiological studies have yielded key clues about the functional organisation of the so-called 'GnRH pulse generator', only in the last decade have the molecular components of the circuitry upstream from GnRH begun to be elucidated. A major contributor to this has… CONTINUE READING

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