Neurokinin 1 and 2 receptors mediate cholera toxin secretion in rat jejunum.

@article{Turvill2000Neurokinin1A,
  title={Neurokinin 1 and 2 receptors mediate cholera toxin secretion in rat jejunum.},
  author={James L. Turvill and Phillip Connor and M. Farthing},
  journal={Gastroenterology},
  year={2000},
  volume={119 4},
  pages={1037-44}
}
BACKGROUND & AIMS Substance P, a member of the tachykinin family, is a prosecretory neuropeptide distributed widely throughout the enteric nervous system. Implicated in inflammatory states, its role in enterotoxigenic water and electrolyte secretion is unclear. We assessed the effect of substance P antagonists and neurokinin receptor antagonists on cholera toxin-, Escherichia coli heat-labile enterotoxin (LT)-, and heat-stable enterotoxin (STa)-induced water secretion in an in vivo rat jejunal… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 42 references

Intracellular mediators of intestinal electrolyte transport

  • EB Chang, MC Rao
  • In: Field M, ed. Diarrheal diseases. New York…
  • 1991
Highly Influential
8 Excerpts

Modes of action of enterotoxin from Vibrio cholerae and Escherichia coli

  • M. Field
  • Rev Infect Dis 1979;1:918–925
  • 1979
Highly Influential
8 Excerpts

5-HT3 antagonist, granisetron, directly inhibits cholera toxin (CT)-induced 5-HT release from enterochromaffin cells

  • JL Turvill, P Connor, MJG. Farthing
  • Gastroenterology 1998;114:A426. Received January
  • 1999

Similar Papers

Loading similar papers…