Neuroinflammation in animal models of traumatic brain injury.

  title={Neuroinflammation in animal models of traumatic brain injury.},
  author={Chong-Chi Chiu and Yi-En Liao and L Y Yang and Jing-Ya Wang and David Tweedie and Hanuma Kumar Karnati and Nigel H. Greig and Jia-yi Wang},
  journal={Journal of neuroscience methods},
Traumatic brain injury (TBI) is a leading cause of mortality and morbidity worldwide. Neuroinflammation is prominent in the short and long-term consequences of neuronal injuries that occur after TBI. Neuroinflammation involves the activation of glia, including microglia and astrocytes, to release inflammatory mediators within the brain, and the subsequent recruitment of peripheral immune cells. Various animal models of TBI have been developed that have proved valuable to elucidate the… CONTINUE READING
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