Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention

@article{Tansey2010NeuroinflammationIP,
  title={Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention},
  author={Mal{\'u} G Tansey and Matthew S. Goldberg},
  journal={Neurobiology of Disease},
  year={2010},
  volume={37},
  pages={510-518}
}
Parkinson's disease (PD) is the second most common neurodegenerative disease, after Alzheimer's disease. The potential causes of PD remain uncertain, but recent studies suggest neuroinflammation and microglia activation play important roles in PD pathogenesis. Major unanswered questions include whether protein aggregates cause the selective loss of dopaminergic neurons in the substantia nigra that underlies the clinical symptoms and whether neuroinflammation is a consequence or a cause of… CONTINUE READING
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