Neuroinflammation after Traumatic Injury to the Developing Brain

  title={Neuroinflammation after Traumatic Injury to the Developing Brain},
  author={Vanya Goranova and Marco Sifringer and Stefanie Endesfelder and Chrysanthy Ikonomidou},
RESULTS: Apoptotic neuronal cell death detected by TUNEL was found at distant regions to trauma site mainly ipsilateral from 6 h to 5 days later. A substantial activation of ED1+ microglia occurred at the site of primary and secondary damages. It was first evident at 12 h, peaked at 36-48 h and decreased significantly after 5 days. A marked increase of mRNA… CONTINUE READING