Neuroimmunophilin ligands: evaluation of their therapeutic potential for the treatment of neurological disorders.

@article{Gold2000NeuroimmunophilinLE,
  title={Neuroimmunophilin ligands: evaluation of their therapeutic potential for the treatment of neurological disorders.},
  author={Bruce G. Gold},
  journal={Expert opinion on investigational drugs},
  year={2000},
  volume={9 10},
  pages={2331-42}
}
  • Bruce G. Gold
  • Published 2000 in Expert opinion on investigational drugs
Neuroimmunophilin ligands are a class of compounds that hold great promise for the treatment of nerve injuries and neurological disease. In contrast to neurotrophins (e.g., nerve growth factor), these compounds readily cross the blood-brain barrier, being orally effective in a variety of animal models of ischaemia, traumatic nerve injury and human neurodegenerative disorders. A further distinction is that neuroimmunophilin ligands act via unique receptors that are unrelated to the classical… CONTINUE READING

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