Neuroimmunological processes in Parkinson's disease and their relation to α-synuclein: microglia as the referee between neuronal processes and peripheral immunity

@inproceedings{SanchezGuajardo2013NeuroimmunologicalPI,
  title={Neuroimmunological processes in Parkinson's disease and their relation to
α-synuclein: microglia as the referee between neuronal processes and peripheral
immunity},
  author={Vanesa Sanchez-Guajardo and Christopher J. Barnum and Mal{\'u} G. Tansey and Marina Romero-Ramos},
  booktitle={ASN neuro},
  year={2013}
}
The role of neuroinflammation and the adaptive immune system in PD (Parkinson's disease) has been the subject of intense investigation in recent years, both in animal models of parkinsonism and in post-mortem PD brains. However, how these processes relate to and modulate α-syn (α-synuclein) pathology and microglia activation is still poorly understood. Specifically, how the peripheral immune system interacts, regulates and/or is induced by neuroinflammatory processes taking place during PD is… CONTINUE READING

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