Neuroimmunoendocrine interactions in post-traumatic stress disorder: focus on long-term implications of childhood maltreatment.

@article{Wieck2014NeuroimmunoendocrineII,
  title={Neuroimmunoendocrine interactions in post-traumatic stress disorder: focus on long-term implications of childhood maltreatment.},
  author={Andr{\'e}a Wieck and Rodrigo Grassi-Oliveira and Carine Hartmann do Prado and Ant{\^o}nio L{\'u}cio Teixeira and Mois{\'e}s Evandro Bauer},
  journal={Neuroimmunomodulation},
  year={2014},
  volume={21 2-3},
  pages={
          145-51
        }
}
Childhood maltreatment has been linked to enhanced vulnerability to psychiatric pathologies in adult life, including post-traumatic stress disorder (PTSD). Previous works have reported cogent neuroendocrine and immune changes related to adult traumatic events (war survivors, refugees, etc.), but little information is known regarding the impact of early-life stress (ELS) in adult physiology. Here, we review the neuroendocrine and immunological changes commonly observed in PTSD, focusing on the… CONTINUE READING

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