Neuroimaging of Natalizumab Complications in Multiple Sclerosis: PML and Other Associated Entities

@inproceedings{Honce2015NeuroimagingON,
  title={Neuroimaging of Natalizumab Complications in Multiple Sclerosis: PML and Other Associated Entities},
  author={Justin Morris Honce and L{\'i}dia Mayumi Nagae and Eric MacKenzie Nyberg},
  booktitle={Multiple sclerosis international},
  year={2015}
}
Natalizumab (Tysabri) is a monoclonal antibody (α4 integrin antagonist) approved for treatment of multiple sclerosis, both for patients who fail therapy with other disease modifying agents and for patients with aggressive disease. Natalizumab is highly effective, resulting in significant decreases in rates of both relapse and disability accumulation, as well as marked decrease in MRI evidence of disease activity. As such, utilization of natalizumab is increasing, and the presentation of its… CONTINUE READING