Neuroimaging biomarkers in bipolar disorder.

  title={Neuroimaging biomarkers in bipolar disorder.},
  author={Josselin Houenou and Marc-Antoine d’Albis and François-Eric Vederine and Chantal Henry and Marion Leboyer and Mich{\`e}le Wessa},
  journal={Frontiers in bioscience},
There is an urgent need to identify objective biomarkers for the assessment of bipolar disorder, to improve diagnosis and prognostic evaluation. Neuroimaging is a particularly promising approach. We review here the structural and functional neuroimaging studies carried out on bipolar disorder. These studies have led to the development of neurobiological models of bipolar disorder assuming cortical-limbic dysregulation. Dorsal brain structures are thought to decrease in volume and activity in… 

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