Neuroimaging and genetic assessment for early diagnosis of Alzheimer's disease.

  title={Neuroimaging and genetic assessment for early diagnosis of Alzheimer's disease.},
  author={G. W. Small},
  journal={The Journal of clinical psychiatry},
  volume={57 Suppl 14},
  • G. W. Small
  • Published 1996 in The Journal of clinical psychiatry
Identifying persons with mild cognitive complaints who are at risk for Alzheimer's disease (AD) will enable the start of antidementia treatments before extensive brain damage develops. Recent research developments link the apolipoprotein E-4 (APOE-4) allele to late-onset familial and late-onset sporadic AD. Studies of relatives at risk for familial AD using brain imaging (positron emission tomography [PET]) and genetic assessments suggest that relatives with the APOE-4 allele have lower… CONTINUE READING
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