Neuroimaging Findings in Mild Traumatic Brain Injury *

@article{McAllister2001NeuroimagingFI,
  title={Neuroimaging Findings in Mild Traumatic Brain Injury *},
  author={Thomas W. McAllister and Molly B. Sparling and Laura A. Flashman and Andrew J. Saykin},
  journal={Journal of Clinical and Experimental Neuropsychology},
  year={2001},
  volume={23},
  pages={775 - 791}
}
The role of neuroimaging in the diagnosis and management of mild traumatic brain injury (TBI) is evolving. In general, the structural imaging techniques play a role in acute diagnosis and management, while the functional imaging techniques show promise for clarification of pathophysiology, symptom genesis, and mechanisms of recovery. A wide array of neuropathological processes are involved in mild TBI including changes in bone (e.g., a skull fracture), tissue density and water content (edema… 
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Cerebral Hemodynamic Changes of Mild Traumatic Brain Injury at the Acute Stage
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The increased CBF combined with increased venous oxygenation suggests an increase in cerebral blood flow that exceeds the oxygen demand of the tissue, in contrast to the regional hypoxia seen in more severe TBI.
Neuroimaging in traumatic brain imaging
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Neuroimaging techniques have become an important part of the diagnostic work up of TBI patients and can determine the presence and extent of injury and guide surgical planning and minimally invasive interventions.
Functional MRI in the Investigation of Blast-Related Traumatic Brain Injury
TLDR
Suggestions and considerations in the development of fMRI studies for the investigation of blast-related traumatic brain injury are presented and considerations that must be made are presented, given the heterogeneous nature of bTBI and its high rate of comorbidity with other physical and psychological injuries.
13 Neuroimaging for Traumatic Brain Injury
TLDR
The sensitivity and specificity of MRI for brain injury is generally superior to CT, although most studies have been retrospective and few direct comparisons have been performed in the recent decade.
Hybrid Diffusion Imaging in Mild Traumatic Brain Injury
TLDR
The NODDI-derived axonal density index and q-space measure for tissue restriction demonstrated superior sensitivity to white matter changes shortly after mTBI.
Neuroimaging and traumatic brain injury: State of the field and voids in translational knowledge
Mild Traumatic Brain Injury Results in Extensive Neuronal Degeneration in the Cerebral Cortex
TLDR
The results indicate that, although mTBI caused only a mild extent of cell death, it led to extensive dendrite degeneration and synapse reduction in the cortex in this model, and suggests that neurodegeneration may be a novel target for developing diagnostic methods and therapeutic approaches for m TBI.
The molecular pathophysiology of concussive brain injury.
Susceptibility weighted imaging: neuropsychologic outcome and pediatric head injury.
The Molecular Pathophysiology of Concussive Brain Injury - an Update.
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