Neuroimaging Evidence of Major Morpho-Anatomical and Functional Abnormalities in the BTBR T+TF/J Mouse Model of Autism

@inproceedings{Dodero2013NeuroimagingEO,
  title={Neuroimaging Evidence of Major Morpho-Anatomical and Functional Abnormalities in the BTBR T+TF/J Mouse Model of Autism},
  author={Luca Dodero and Mario Damiano and Alberto Galbusera and Angelo Bifone and Sotirios A. Tsaftsaris and Maria Luisa Scattoni and Alessandro Gozzi},
  booktitle={PloS one},
  year={2013}
}
BTBR T+tf/J (BTBR) mice display prominent behavioural deficits analogous to the defining symptoms of autism, a feature that has prompted a widespread use of the model in preclinical autism research. Because neuro-behavioural traits are described with respect to reference populations, multiple investigators have examined and described the behaviour of BTBR mice against that exhibited by C57BL/6J (B6), a mouse line characterised by high sociability and low self-grooming. In an attempt to probe… CONTINUE READING
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