Neurohormonal, hemodynamic, and electrocardiographic evaluations of healthy dogs receiving long-term administration of doxorubicin.

@article{Souza2006NeurohormonalHA,
  title={Neurohormonal, hemodynamic, and electrocardiographic evaluations of healthy dogs receiving long-term administration of doxorubicin.},
  author={Rute Chami{\'e} Alves de Souza and Aparecido Ant{\^o}nio Camacho},
  journal={American journal of veterinary research},
  year={2006},
  volume={67 8},
  pages={1319-25}
}
OBJECTIVE To evaluate diagnostic testing that could be used to establish an early diagnosis of cardiotoxicosis induced by long-term administration of doxorubicin. ANIMALS 13 adult mixed-breed dogs. Procedures-7 dogs were administered doxorubicin chloride (30 mg/m(2), IV, q 21 d for 168 days [cumulative dose, 240 mg/m(2)]), and 6 dogs received saline (0.9… CONTINUE READING