Neurogenic acceleration of degenerative joint lesions.

  title={Neurogenic acceleration of degenerative joint lesions.},
  author={Brian L O'Connor and M J Palmoski and Kenneth D. Brandt},
  journal={The Journal of bone and joint surgery. American volume},
  volume={67 4},
A severe form of degenerative joint lesion (neuropathic arthropathy) is known to complicate a variety of diseases that are associated with sensory abnormalities. We studied the relationship between sensory deficits and the development of degenerative joint lesions in dogs in two complementary experiments. In Experiment 1, dogs that were subjected to unilateral dorsal-root ganglionectomy (fourth lumbar to first sacral vertebra) failed to show biochemical, gross, or histological evidence of… CONTINUE READING