Neurogenic Model of Migraine

@article{Buzzi1995NeurogenicMO,
  title={Neurogenic Model of Migraine},
  author={M. Gabriella Buzzi and Michela Bonamini and MA Moskowitz},
  journal={Cephalalgia},
  year={1995},
  volume={15},
  pages={277 - 280}
}
Activation of peripheral trigeminal fibers induces neurogenic inflammation in rat dura mater, as well as vascular and mast cell changes. These changes parallel an increase of vasodilating and permeability promoting peptides in venous effluent of the cephalic circulation. The experimental model of electrical trigeminal ganglion stimulation or systemic capsaicin administration has proven effective in detecting cellular activation in brainstem trigeminal nuclei. Animal experimental models of… 

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