Neurogenic Dilator and Constrictor Responses of Pial Arteries in Vitro


Two distinct responses to transmural electrical stimulation of cerebrovascular smooth muscle isolated from dogs and sheep have been identified. Both these responses were blocked with tetrodotoiin and therefore were attributed to stimulation of intramural nerves. A constrictor response to transmural nerve stimulation (TNS) which was blocked with guanethidine… (More)


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