Neurogenetics of depression: a focus on reward processing and stress sensitivity.

@article{Bogdan2013NeurogeneticsOD,
  title={Neurogenetics of depression: a focus on reward processing and stress sensitivity.},
  author={Ryan Bogdan and Yuliya S Nikolova and Diego A. Pizzagalli},
  journal={Neurobiology of disease},
  year={2013},
  volume={52},
  pages={12-23}
}
Major depressive disorder (MDD) is etiologically complex and has a heterogeneous presentation. This heterogeneity hinders the ability of molecular genetic research to reliably detect the small effects conferred by common genetic variation. As a result, significant research efforts have been directed at investigating more homogenous intermediate phenotypes believed to be more proximal to gene function and lie between genes and/or environmental effects and disease processes. In the current review… CONTINUE READING