Neurogenesis in the adult brain: new strategies for central nervous system diseases.

  title={Neurogenesis in the adult brain: new strategies for central nervous system diseases.},
  author={Dieter Chichung Lie and Hongjun Song and Sophia A. Colamarino and Guo-li Ming and Fred H. Gage},
  journal={Annual review of pharmacology and toxicology},
New cells are continuously generated from immature proliferating cells throughout adulthood in many organs, thereby contributing to the integrity of the tissue under physiological conditions and to repair following injury. In contrast, repair mechanisms in the adult central nervous system (CNS) have long been thought to be very limited. However, recent findings have clearly demonstrated that in restricted areas of the mammalian brain, new functional neurons are constantly generated from neural… 

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