Neurogenesis in neonatal rat brain is regulated by peripheral injection of basic fibroblast growth factor (bFGF).

@article{Tao1996NeurogenesisIN,
  title={Neurogenesis in neonatal rat brain is regulated by peripheral injection of basic fibroblast growth factor (bFGF).},
  author={Yu Ting Tao and Ira B. Black and Emanuel Dicicco-Bloom},
  journal={The Journal of comparative neurology},
  year={1996},
  volume={376 4},
  pages={653-63}
}
Many major diseases of human brain involve deficiencies of select neuronal populations. As one approach to repair, we examined regulation of neurogenesis directly in vivo, employing postnatal day 1 (P1) cerebellar cortex, which is composed primarily of granule neurons and dividing precursors. We focused on basic fibroblast growth factor (bFGF), which stimulates precursor mitosis in culture and which is highly expressed in cerebellum during neurogenesis. Subcutaneous injection of bFGF increased… CONTINUE READING
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