Neurogenesis in cerebral heterotopia induced in rats by prenatal methylazoxymethanol treatment.

@article{Battaglia2003NeurogenesisIC,
  title={Neurogenesis in cerebral heterotopia induced in rats by prenatal methylazoxymethanol treatment.},
  author={Giorgio Stefano Battaglia and Silvia Pagliardini and Laura Saglietti and Flaminio Cattabeni and Monica di Luca and Stefania Bassanini and Veronica Setola},
  journal={Cerebral cortex},
  year={2003},
  volume={13 7},
  pages={736-48}
}
We have previously demonstrated that the antiproliferative agent methylazoxymethanol acetate (MAM) is able to induce in rats cerebral heterotopia that share striking similarities with those observed in human periventricular nodular heterotopia (PNH), a cerebral dysgenesis frequently observed in human patients affected by drug-resistant focal epilepsy. In… CONTINUE READING