Neurofilament polymer transport in axons.

@article{Yan2005NeurofilamentPT,
  title={Neurofilament polymer transport in axons.},
  author={Yanping Yan and Anthony Brown},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2005},
  volume={25 30},
  pages={
          7014-21
        }
}
Neurofilament proteins are known to be transported along axons by slow axonal transport, but the form in which they move is controversial. In previous studies on cultured rat sympathetic neurons, we found that green fluorescent protein-tagged neurofilament proteins move predominantly in the form of filamentous structures, and we proposed that these structures are single-neurofilament polymers. In the present study, we have tested this hypothesis by using a rapid perfusion technique to capture… CONTINUE READING

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