Neurofilament and glial fibrillary acidic protein in multiple sclerosis.

@article{Norgren2004NeurofilamentAG,
  title={Neurofilament and glial fibrillary acidic protein in multiple sclerosis.},
  author={Niklas Norgren and Peter Sundstr{\"o}m and Anders Svenningsson and Lars E. Rosengren and Torgny Stigbrand and Martin Gunnarsson},
  journal={Neurology},
  year={2004},
  volume={63 9},
  pages={1586-90}
}
OBJECTIVE To evaluate levels of neurofilament light (NFL) and glial fibrillary acidic protein (GFAP) in CSF from patients with multiple sclerosis (MS) in relation to clinical progress of the disease. METHODS CSF levels of NFL and GFAP were determined by sensitive ELISAs in 99 patients with different subtypes of MS, classified in terms of "ongoing relapse" or "clinically stable disease," and 25 control subjects. Levels were compared with paraclinical data such as immunoglobulin G index and… CONTINUE READING