Neurofilament 68 and neurofilament 200 protein levels decrease after traumatic brain injury.

@article{Posmantur1994Neurofilament6A,
  title={Neurofilament 68 and neurofilament 200 protein levels decrease after traumatic brain injury.},
  author={R. M. Posmantur and Ronald L. Hayes and C Edward Dixon and William C. Taft},
  journal={Journal of neurotrauma},
  year={1994},
  volume={11 5},
  pages={533-45}
}
We have examined the effect of lateral cortical impact injury on the levels of axonal cytoskeletal proteins in adult rats. Traumatic brain injury (TBI) causes a significant decrease in the protein levels of two prominent neurofilament (NF) proteins, NF68 and NF200. We employed quantitative immunoreactivity measurements on Western blots to examine NF68 and NF200 levels in homogenates of hippocampal and cortical tissue taken at several intervals postinjury. Sham injury had no effect on NF protein… CONTINUE READING