Neurofibromin homologs Ira1 and Ira2 affect glycerophosphoinositol production and transport in Saccharomyces cerevisiae.

Abstract

Saccharomyces cerevisiae produces extracellular glycerophosphoinositol through phospholipase-mediated turnover of phosphatidylinositol and transports glycerophosphoinositol into the cell upon nutrient limitation. A screening identified the RAS GTPase-activating proteins Ira1 and Ira2 as required for utilization of glycerophosphoinositol as the sole… (More)
DOI: 10.1128/EC.00217-09

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@article{Bishop2009NeurofibrominHI, title={Neurofibromin homologs Ira1 and Ira2 affect glycerophosphoinositol production and transport in Saccharomyces cerevisiae.}, author={Andrew C Bishop and Beth A Surlow and P. Shanmukha Anand and Katherine Hofer and Matthew M. Henkel and Jana Patton-Vogt}, journal={Eukaryotic cell}, year={2009}, volume={8 11}, pages={1808-11} }