Neurofibromin and NF1 Gene Analysis in Composite Pheochromocytoma and Tumors Associated with von Recklinghausen’s Disease

@article{Kimura2002NeurofibrominAN,
  title={Neurofibromin and NF1 Gene Analysis in Composite Pheochromocytoma and Tumors Associated with von Recklinghausen’s Disease},
  author={Noriko Kimura and Toshiya Watanabe and Masayuki Fukase and Atsushi Wakita and Takao Noshiro and Itaru Kimura},
  journal={Modern Pathology},
  year={2002},
  volume={15},
  pages={183-188}
}
Composite tumor of pheochromocytoma and neuroblastoma, or ganglioneuroma, or ganglioneuroblastoma (composite pheochromocytoma), also known as mixed neuroendocrine and neural tumor, are sometimes combined with neurofibromatosis type 1 (NF1). To better understand the relationship between NF1 and composite pheochromocytoma, an immunohistochemical study using anti-neuro-fibromin that is an NF1 gene product and DNA sequence of NF1 Exon 31 were carried out in five cases of composite pheochromocytoma… CONTINUE READING
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