Neurofibromatosis type 1 associated with central nervous system lymphoma.

  title={Neurofibromatosis type 1 associated with central nervous system lymphoma.},
  author={Ghassan Zein and Ellen W Yu and Khaled A. Tawansy and Andr{\'a}s Berta and Charles Stephen Foster},
  journal={Ophthalmic genetics},
  volume={25 1},
PURPOSE To report the occurrence of central nervous system (CNS) lymphoma in a patients with neurofibromatosis type 1 (NF1). DESIGN Interventional case report. METHODS A 47-year-old male with a parieto-occipital lobe lesion was referred for ocular evaluation. Skin, brain, and vitreous biopsies were performed. RESULTS The discovery of Lisch nodules of the iris prompted a physical examination that revealed cutaneous stigmata of NF1. Biopsy of the CNS lesion revealed diffuse large B-cell… CONTINUE READING