Neurofibromatosis Type 1 and Autism Spectrum Disorder

  title={Neurofibromatosis Type 1 and Autism Spectrum Disorder},
  author={Shruti Garg and Jonathan Green and Kathy Leadbitter and Richard Emsley and Annukka Lehtonen and D. Gareth R. Evans and Susan Mary Huson},
  pages={e1642 - e1648}
OBJECTIVE: To determine the prevalence of autism spectrum disorder (ASD) in Neurofibromatosis Type 1 (NF1). METHODS: Second-phase population-based epidemiologic study using an allcase NF1 registry in a defined UK 4.1 million population area. A total of 109 (52.7%) of 207 responders from the initial screening phase were grouped by using the parent-rated Social Responsiveness Scale (SRS) as significant ASD (SRS≥76; n = 32), moderate ASD (SRS ≥ 60<76; n = 29), or non-ASD (SRS <60, n = 48). Twenty… 

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