Neurofeedback treatment of epilepsy: from basic rationale to practical application

  title={Neurofeedback treatment of epilepsy: from basic rationale to practical application},
  author={Tobias Egner and Maurice B. Sterman},
  journal={Expert Review of Neurotherapeutics},
  pages={247 - 257}
  • T. Egner, M. Sterman
  • Published 1 February 2006
  • Psychology, Biology, Medicine
  • Expert Review of Neurotherapeutics
The treatment of epilepsy through operant conditioning of the sensorimotor rhythm electroencephalogram has a 35-year history. Neurophysiological studies have shown that this phasic oscillation reflects an inhibitory state of the sensorimotor system. Operant learning of sensory motor rhythm production results in an upregulation of excitation thresholds within the thalamocortical sensory and motor circuitry, which in turn is associated with reduced susceptibility to seizures. The clinical… 

Biofeedback in the treatment of epilepsy

  • M. Sterman
  • Psychology, Biology
    Cleveland Clinic Journal of Medicine
  • 2010
This review traces the application of electroencephalographic (EEG) operant conditioning, or biofeedback, from animal research to its emergence as an alternative treatment for the major types of seizure disorder, resulting in numerous well-controlled group and single-case studies summarized in recent meta-analyses.

Neurofeedback and Basic Learning Theory: Implications for Research and Practice

Brain activity assessed by electroencephalography (EEG) has been demonstrated to respond to conditioning techniques. The concept of modulating this activity has been called EEG biofeedback, more

Comparison of the Effects of Sensorimotor Rhythm and Slow Cortical Potential Neurofeedback in Epilepsy

Preliminary data is supplied to support that SMR neurofeedback training as an intervention should further be explored as a therapeutic option for children who suffer from focal epilepsy.

Neurofeedback treatments enable the EEG-normalization and total seizure control of epilepsy – A Case Study

Two cases of epilepsy patients who were treated with QEEG guided neurofeedback experienced total cessation of seizures at an early stage in the treatment and displayed substantial behavioral and cognitive improvement during the course of treatment.

EEG biofeedback in the treatment of attention deficit hyperactivity disorder.

  • P. Friel
  • Psychology, Biology
    Alternative medicine review : a journal of clinical therapeutic
  • 2007
EEG biofeedback therapy rewards scalp EEG frequencies that are associated with relaxed attention, and suppresses frequencies associated with under- or over-arousal in patients with attention deficit/hyperactivity disorder.

Neurofeedback training on sensorimotor rhythmin marmoset monkeys

Telemetric sensorimotor rhythm (SMR) feedback training in the marmoset monkey is applied to examine the monkey's capability to voluntary control their brain activity, providing the first evidence of nonhuman primates having an operant control over the SMR.

Enduring Effects of Neurofeedback in Children

Meta-Analysis of EEG Biofeedback in Treating Epilepsy

A meta-analysis of existing research on neurofeedback and epilepsy found EEG operant conditioning was found to produce a significant reduction on seizure frequency, especially noteworthy given the patient group, individuals who had been unable to control their seizures with medical treatment.

[Neurofeedback therapy influence on clinical status and some EEG parameters in children with localized epilepsy].

During NF therapy in almost all children with epileptic partial seizures and secondarily generalized seizures resolution or reduction of clinical seizures was observed, and NF therapy advantageously reduced the number of localized changes and decreased sensitivity of EEG pattern to hyperventilation and photostimulation.



Neurofeedback treatment of epilepsy.

EEG Operant Conditioning for Control of Epilepsy

Although a few patients were significantly helped by this training, only 43% of patients showed significant changes in seizure occurrence and a lesser number were felt to have benefited clinically.

Basic Concepts and Clinical Findings in the Treatment of Seizure Disorders with EEG Operant Conditioning

Two issues concerning sensorimotor EEG operant conditioning, or biofeedback, as a therapeutic modality for the treatment of seizure disorders are the focus of this review. The first relates to the

Critical validation studies of neurofeedback.

Biofeedback Training of the Sensorimotor Electroencephalogram Rhythm in Man: Effects on Epilepsy

Training in four epileptic patients, who previously were not controlled by chemotherapy, was accompanied by a significant reduction of EEG and clinical epileptic manifestations, as indicated by sequential power spectral analysis, clinical EEG records, and seizure logs.

Suppression of seizures in an epileptic following sensorimotor EEG feedback training.

  • M. StermanL. Friar
  • Psychology, Biology
    Electroencephalography and clinical neurophysiology
  • 1972

Behavioral management of epileptic seizures following EEG biofeedback training of the sensorimotor rhythm

Eight severely epileptic patients, four males and four females, ranging in age from 10 to 29 years, were trained to increase 12–14 Hz EEG activity from the regions overlying the Rolandic area. This