Neuroendocrinology of Aging: The Potential of Gene Therapy as an Interventive Strategy

@article{Goya2001NeuroendocrinologyOA,
  title={Neuroendocrinology of Aging: The Potential of Gene Therapy as an Interventive Strategy},
  author={R. Goya and F. Bolognani and C. Here{\~n}{\'u} and O. Rimoldi},
  journal={Gerontology},
  year={2001},
  volume={47},
  pages={168 - 173}
}
  • R. Goya, F. Bolognani, +1 author O. Rimoldi
  • Published 2001
  • Biology, Medicine
  • Gerontology
    • Objective: This paper reviews the current status of gene therapy in the neuroendocrine system and discusses the interventive potential of this methodology for neuroendocrine pathologies associated with aging. Background and Results: A brief description is first presented of the viral-vector-based gene delivery systems being currently used in the neuroendocrine system, namely the adenoviral and herpetic (HSV1) vector systems. Next, an account of the neuroendocrine pathologies for which gene… CONTINUE READING
    View on PubMed
    doi.org
    5 Citations
    Highly Influencial Citations
    1
    Background Citations
    1
    5 Citations
    Citation Type

    Citation Type

    Tumores hipofisários: opções terapêuticas atuais e perspectivas futuras de tratamento
    • 2
    • PDF
    Genetic determinants of ageing processes and diseases in later life.
    • 17
    Bowel preparation for colonoscopy may decrease the levels of testosterone in Korean men
    • 1
    • PDF
    Terapia génica en endocrinología: una aproximación realista
    • 1
    • Highly Influenced
    Die Akzeptanz genetischer Untersuchungen durch ältere Menschen
    • 1

    References

    SHOWING 1-10 OF 30 REFERENCES
    Long-term gene therapy in the CNS: Reversal of hypothalamic diabetes insipidus in the Brattleboro rat by using an adenovirus expressing arginine vasopressin
    • 98
    Adenovirus-mediated gene delivery to hypothalamic magnocellular neurons in mice.
    • 15
    • PDF
    Development and application of adenoviral vectors for gene therapy of cancer
    • W. Zhang
    • Biology, Medicine
    • Cancer Gene Therapy
    • 1999
    • 184
    • PDF
    The role of neuronal growth factors in neurodegenerative disorders of the human brain
    • 488
    Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy.
    • 1,641
    • PDF
    Targeted expression of toxic genes directed by pituitary hormone promoters: a potential strategy for adenovirus-mediated gene therapy of pituitary tumors.
    • 70
    • PDF
    Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo
    • 1,083
    Adenovirus-mediated herpes simplex virus type-1 thymidine kinase gene therapy suppresses oestrogen-induced pituitary prolactinomas.
    • 57
    • PDF
    Dopaminergic Neurons Protected from Degeneration by GDNF Gene Therapy
    • 619
    [2] Techniques for human adenovirus vector construction and characterization
    • 128