Neuroendocrine regulation of the corpus luteum in the human. Evidence for pulsatile progesterone secretion.

@article{Filicori1984NeuroendocrineRO,
  title={Neuroendocrine regulation of the corpus luteum in the human. Evidence for pulsatile progesterone secretion.},
  author={Marco Filicori and James P. Butler and William F. Crowley},
  journal={The Journal of clinical investigation},
  year={1984},
  volume={73 6},
  pages={
          1638-47
        }
}
The pattern of episodic gonadotropin release was studied in 15 normal female volunteers during the luteal phase of the menstrual cycle with 24 h of blood sampling for follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels at 10-min intervals. Six subjects (two in the early, two in the mid-, and two in the late luteal phase) also had each of these specimens processed for progesterone levels. A progressive slowing of LH pulsations was present across the luteal phase with the mean… 
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TLDR
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TLDR
Progesterone may, thus, represent the ultimate ovarian signal to the estrogen-primed hypothalamic-pituitary unit to trigger the gonadotropin surge that leads to ovulation by suppressing or antagonizing an ovarian progestational signal.
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