Neuroendocrine profile in a rat model of psychosocial stress: relation to oxidative stress.

@article{Colaianna2013NeuroendocrinePI,
  title={Neuroendocrine profile in a rat model of psychosocial stress: relation to oxidative stress.},
  author={Marilena Colaianna and Stefania Schiavone and Margherita Zotti and Paolo Tucci and Maria Grazia Morgese and Liselotte B{\"a}ckdahl and Rikard Holmdahl and K T Krause and Vincenzo Cuomo and Luigia Trabace},
  journal={Antioxidants & redox signaling},
  year={2013},
  volume={18 12},
  pages={1385-99}
}
AIMS Psychosocial stress alters the hypothalamic-pituitary-adrenal axis (HPA-axis). Increasing evidence shows a link between these alterations and oxidant elevation. Oxidative stress is implicated in the stress response and in the pathogenesis of neurologic and psychiatric diseases. NADPH oxidases (NOXs) are a major source of reactive oxygen species (ROS) in the central nervous system. Here, we investigated the contributory role of NOX2-derived ROS to the development of neuroendocrine… CONTINUE READING