Neuroendocrine mechanisms and the precipitation of depression by life events.

@article{Checkley1992NeuroendocrineMA,
  title={Neuroendocrine mechanisms and the precipitation of depression by life events.},
  author={S. Checkley},
  journal={The British journal of psychiatry. Supplement},
  year={1992},
  volume={15},
  pages={
          7-17
        }
}
  • S. Checkley
  • Published 1992
  • Psychology, Medicine
  • The British journal of psychiatry. Supplement
It is now generally accepted that stressful life events and chronic difficulties can trigger the onset of depression in predisposed individuals. However, although much is known of the neurobiology of stress, few attempts have been made to provide a biological explanation for the mechanisms whereby life events might trigger depression. Enough is now known of the central control of hypothalamic pituitary adrenal (HPA) function and its response to stress to permit an examination of its role in the… Expand
78 Citations
Glucocorticoids and the genesis of depressive illness. A psychobiological model.
  • T. Dinan
  • Psychology, Medicine
  • The British journal of psychiatry : the journal of mental science
  • 1994
  • 326
  • PDF
Stress, ageing and dementia
  • 3
Dysthymia: a review of pharmacological and behavioral factors
  • 78
  • PDF
The neuroendocrinology of depression and chronic stress.
  • 308
  • PDF
Behavioral and neurobiological consequences of prolonged glucocorticoid exposure in rats: Relevance to depression
  • 193
...
1
2
3
4
5
...