Neuroendocrine-immune system interactions and autoimmunity.

  title={Neuroendocrine-immune system interactions and autoimmunity.},
  author={Ronald L. Wilder},
  journal={Annual review of immunology},
The concept of an integrated bidirectionally regulated neuroendocrine-immune adaptive response to stress has strong experimental support. The quality and intensity of this coordinated response to stress varies depending upon age, gender, reproductive status, and other genetically determined factors as well as the types and magnitudes of environmental challenges. These factors and dysfunctional communication between the nervous, endocrine, and immune systems appear to contribute to the… CONTINUE READING


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