Neuroendocrine function in adult female transgenic mice expressing the human growth hormone gene.

Abstract

Adult female transgenic mice expressing the human GH (hGH) gene with mouse metallothionein-I promoter are sterile. To evaluate the hypothalamic-pituitary function in these animals, adult female transgenic mice and nontransgenic normal littermates were ovariectomized. On days 7 and 8 after ovariectomy, mice were injected with either oil or primed with 0.5… (More)

Topics

Cite this paper

@article{Chandrashekar1992NeuroendocrineFI, title={Neuroendocrine function in adult female transgenic mice expressing the human growth hormone gene.}, author={Varadaraj Chandrashekar and Andrzej Bartke and T. E. Wagner}, journal={Endocrinology}, year={1992}, volume={130 4}, pages={1802-8} }