Neuroendocrine factors regulate retinoic acid receptors in normal and hypoplastic lung development.

@article{PereiraTerra2015NeuroendocrineFR,
  title={Neuroendocrine factors regulate retinoic acid receptors in normal and hypoplastic lung development.},
  author={Patr{\'i}cia Pereira-Terra and Rute Silva Moura and Cristina Nogueira-Silva and Jorge Correia-Pinto},
  journal={The Journal of physiology},
  year={2015},
  volume={593 15},
  pages={3301-11}
}
KEY POINTS Retinoic acid (RA) and ghrelin levels are altered in human hypoplastic lungs when compared to healthy lungs. Although considerable data have been obtained about RA, ghrelin and bombesin in the congenital diaphragmatic hernia (CDH) rat model, neuroendocrine factors have never been associated with the RA signalling pathway in this animal model. In this study, the interaction between neuroendocrine factors and RA was explored in the CDH rat model. The authors found that normal fetal… CONTINUE READING