Neuroendocrine control of thymus physiology.

@article{Savino2000NeuroendocrineCO,
  title={Neuroendocrine control of thymus physiology.},
  author={Wilson Savino and Mireille Dardenne},
  journal={Endocrine reviews},
  year={2000},
  volume={21 4},
  pages={412-43}
}
The thymus gland is a central lymphoid organ in which bone marrow-derived T cell precursors undergo differentiation, eventually leading to migration of positively selected thymocytes to the peripheral lymphoid organs. This differentiation occurs along with cell migration in the context of the thymic microenvironment, formed of epithelial cells, macrophages, dendritic cells, fibroblasts, and extracellular matrix components. Various interactions occurring between microenvironmental cells and… CONTINUE READING

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