Neuroendocrine control of thymic hormonal production. I. Prolactin stimulates in vivo and in vitro the production of thymulin by human and murine thymic epithelial cells.

@article{Dardenne1989NeuroendocrineCO,
  title={Neuroendocrine control of thymic hormonal production. I. Prolactin stimulates in vivo and in vitro the production of thymulin by human and murine thymic epithelial cells.},
  author={Mireille Dardenne and Wilson Savino and M C Gagnerault and Tomoko Itoh and Jean François Bach},
  journal={Endocrinology},
  year={1989},
  volume={125 1},
  pages={
          3-12
        }
}
The thymic epithelium is responsible for the secretion of thymic peptides, which intervene in some steps of intra- and extrathymic T cell differentiation. Recent data suggest that thymic hormone secretion is modulated by the neuroendocrine network, comprising thyroid, adrenals, and gonads. However, the role of the pituitary gland in this regulation is still poorly understood. In the present paper we studied the in vivo and in vitro influences of PRL on the secretion of thymulin, one of the… CONTINUE READING

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