Neuroendocrine control of reproductive aging: roles of GnRH neurons.

@article{Yin2006NeuroendocrineCO,
  title={Neuroendocrine control of reproductive aging: roles of GnRH neurons.},
  author={Weiling Yin and Andrea C Gore},
  journal={Reproduction},
  year={2006},
  volume={131 3},
  pages={
          403-14
        }
}
The process of reproductive senescence in many female mammals, including humans, is characterized by a gradual transition from regular reproductive cycles to irregular cycles to eventual acyclicity, and ultimately a loss of fertility. In the present review, the role of the hypothalamic gonadotropin-releasing hormone (GnRH) neurons is considered in this context. GnRH neurons provide the primary driving force upon the other levels of the reproductive axis. With respect to aging, GnRH cells… CONTINUE READING

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