Neuroendocrine and immune network re-modeling in chronic fatigue syndrome: an exploratory analysis.

@article{Fuite2008NeuroendocrineAI,
  title={Neuroendocrine and immune network re-modeling in chronic fatigue syndrome: an exploratory analysis.},
  author={Jim Fuite and Suzanne D. Vernon and Gordon Broderick},
  journal={Genomics},
  year={2008},
  volume={92 6},
  pages={393-9}
}
This work investigates the significance of changes in association patterns linking indicators of neuroendocrine and immune activity in patients with chronic fatigue syndrome (CFS). Gene sets preferentially expressed in specific immune cell isolates were integrated with neuroendocrine data from a large population-based study. Co-expression patterns linking immune cell activity with hypothalamic-pituitary-adrenal (HPA), thyroidal (HPT) and gonadal (HPG) axis status were computed using mutual… CONTINUE READING
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