Neuroendocrine Morbidity After Pediatric Optic Gliomas: A Longitudinal Analysis of 166 Children Over 30 Years.

@article{Gan2015NeuroendocrineMA,
  title={Neuroendocrine Morbidity After Pediatric Optic Gliomas: A Longitudinal Analysis of 166 Children Over 30 Years.},
  author={Hoong-Wei Gan and Kim P. Phipps and Kristian Aquilina and Mark Nicholas Gaze and Richard D Hayward and Helen Alexandra Spoudeas},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2015},
  volume={100 10},
  pages={3787-99}
}
CONTEXT Fifty percent of pediatric low-grade gliomas affect the optic pathway, hypothalamus, and suprasellar areas (OP/HSGs), resulting in significant long-term neuroendocrinopathy. OBJECTIVE This study aimed to dissect tumor- from treatment-related risk factors for OP/HSG-associated neuroendocrinopathy. DESIGN This was a retrospective case notes analysis of 166 children with newly diagnosed OP/HSGs at our quaternary center between 1980 and 2010 by multivariate Cox, linear, and logistic… CONTINUE READING
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