Neurodevelopmental dysfunction among nonreferred children with idiopathic megalencephaly.

  title={Neurodevelopmental dysfunction among nonreferred children with idiopathic megalencephaly.},
  author={Adrian D. Sandler and Martin Knudsen and Todd T. Brown and Richard M. Christian},
  journal={The Journal of pediatrics},
  volume={131 2},
PURPOSE To determine whether nonreferred children with idiopathic megalencephaly show evidence of specific neurodevelopmental dysfunction compared with sibling control subjects and age-matched control subjects. DESIGN Cross-sectional, case-control study in a large, suburban pediatric practice. Subjects included 20 children between the ages of 6 and 15 years with a head circumference at greater than the 98th percentile, 19 siblings of these children with normalsize heads, and 16 age-matched… CONTINUE READING