Neurodevelopmental disorders as a cause of seizures: neuropathologic, genetic, and mechanistic considerations.

@article{Crino2002NeurodevelopmentalDA,
  title={Neurodevelopmental disorders as a cause of seizures: neuropathologic, genetic, and mechanistic considerations.},
  author={Peter B. Crino and Hajime Miyata and H V Vinters},
  journal={Brain pathology},
  year={2002},
  volume={12 2},
  pages={212-33}
}
This review will consider patterns of developmental neuropathologic abnormalities-malformations of cortical development (MCD)--encountered in infants (often with infantile spasms), children, and adults with intractable epilepsy. Treatment of epilepsy associated with some MCD, such as focal cortical dysplasia and tubers of tuberous sclerosis, may include cortical resection performed to remove the "dysplastic" region of cortex. In extreme situations (eg, hemimegalencephaly), hemispherectomy may… CONTINUE READING

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