Neurodevelopmental disorders: mechanisms and boundary definitions from genomes, interactomes and proteomes

@inproceedings{Mullin2013NeurodevelopmentalDM,
  title={Neurodevelopmental disorders: mechanisms and boundary definitions from genomes, interactomes and proteomes},
  author={Ariana P. Mullin and Anagha Gokhale and Andres Moreno-De-Luca and Swastika Sanyal and John L Waddington and Victor Faundez},
  booktitle={Translational Psychiatry},
  year={2013}
}
Neurodevelopmental disorders such as intellectual disability, autism spectrum disorder and schizophrenia lack precise boundaries in their clinical definitions, epidemiology, genetics and protein–protein interactomes. This calls into question the appropriateness of current categorical disease concepts. Recently, there has been a rising tide to reformulate neurodevelopmental nosological entities from biology upward. To facilitate this developing trend, we propose that identification of unique… CONTINUE READING