Neurodegenerative Disease: Rescuing memory


has shown that upregulation of brainderived neurotrophic factor (BDNF), using a compound that modulates glutamate receptors, improves memory impairments in a mouse model of Huntington’s disease (HD). HD is caused by a CAG repeat expansion in HTT, the gene that encodes the huntingtin protein, and is characterized by severe motor defects, as well as cognitive… (More)
DOI: 10.1038/nrd2882