Neurodegeneration in schizophrenia.

  title={Neurodegeneration in schizophrenia.},
  author={Trevor Archer},
  journal={Expert review of neurotherapeutics},
  volume={10 7},
The neurodegenerative aspect of schizophrenia presupposes gene-environmental interactions involving chromosomal abnormalities and obstetric/perinatal complications that culminate in predispositions that impart a particular vulnerability for drastic and unpredictable precipitating factors, such as stress or chemical agents. The notion of a neurodevelopmental progression to the disease state implies that early developmental insults, with neurodegenerative proclivities, evolve into structural… CONTINUE READING


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