Neurocomputational models of working memory

@article{Durstewitz2000NeurocomputationalMO,
  title={Neurocomputational models of working memory},
  author={D. Durstewitz and J. Seamans and T. Sejnowski},
  journal={Nature Neuroscience},
  year={2000},
  volume={3 Suppl 1},
  pages={1184-1191}
}
  • D. Durstewitz, J. Seamans, T. Sejnowski
  • Published 2000
  • Medicine, Psychology
  • Nature Neuroscience
  • During working memory tasks, the firing rates of single neurons recorded in behaving monkeys remain elevated without external cues. Modeling studies have explored different mechanisms that could underlie this selective persistent activity, including recurrent excitation within cell assemblies, synfire chains and single-cell bistability. The models show how sustained activity can be stable in the presence of noise and distractors, how different synaptic and voltage-gated conductances contribute… CONTINUE READING
    641 Citations

    Figures and Topics from this paper.

    Explore Further: Topics Discussed in This Paper

    Emergence of task-dependent representations in working memory circuits
    • 9
    • PDF
    Working memory and spontaneous activity of cell assemblies. A biologically motivated computational model
    • C. Molter, David Colliaux, Y. Yamaguchi
    • Mathematics, Computer Science
    • 2008 IEEE International Joint Conference on Neural Networks (IEEE World Congress on Computational Intelligence)
    • 2008
    • 4
    Balanced cortical microcircuitry for maintaining information in working memory
    • 133
    • Highly Influenced
    • PDF
    Dynamics and plasticity of stimulus-selective persistent activity in cortical network models.
    • N. Brunel
    • Medicine, Psychology
    • Cerebral cortex
    • 2003
    • 85
    • PDF
    A neurodynamical model for working memory
    • 64
    • PDF
    A Spiking Working Memory Model Based on Hebbian Short-Term Potentiation
    • 44
    • PDF
    Mechanisms of Persistent Activity in Cortical Circuits: Possible Neural Substrates for Working Memory.
    • 69
    WORKING MEMORY AND TEMPORAL PATTERNS: THE IMPLICATIONS OF NEURAL POPULATIONS

    References

    SHOWING 1-10 OF 93 REFERENCES
    A spiking network model of short-term active memory
    • 269
    • PDF
    A Neurocomputational Theory of the Dopaminergic Modulation of Working Memory Functions
    • 234
    • PDF
    Synaptic Basis of Cortical Persistent Activity: the Importance of NMDA Receptors to Working Memory
    • X. J. Wang
    • Medicine, Biology
    • The Journal of Neuroscience
    • 1999
    • 727
    • PDF
    Paradigmatic Working Memory (Attractor) Cell in IT Cortex
    • 63
    • PDF