Neurocognitive endophenotypes in a multiplex multigenerational family study of schizophrenia.

@article{Gur2007NeurocognitiveEI,
  title={Neurocognitive endophenotypes in a multiplex multigenerational family study of schizophrenia.},
  author={Raquel E. Gur and Vishwajit L. Nimgaonkar and Laura Almasy and Monica E. Calkins and John Daniel Ragland and Michael F. Pogue-Geile and Stephen J. Kanes and John Blangero and Ruben C. Gur},
  journal={The American journal of psychiatry},
  year={2007},
  volume={164 5},
  pages={813-9}
}
OBJECTIVE Genetic factors contribute to the development of schizophrenia where cognitive dysfunction is a hallmark. The purpose of this article was to examine computerized neurocognitive measures as candidate endophenotypic markers of liability for schizophrenia in a genetically informative cohort. METHOD European Americans from 35 multiplex multigenerational families (N=349) and healthy participants (N=154) underwent clinical assessments and neurocognitive measurements and provided blood… CONTINUE READING
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